diff --git a/scripts/run-full-tests b/scripts/run-full-tests
index ca2f5a7d3..47e4f5f7b 100755
--- a/scripts/run-full-tests
+++ b/scripts/run-full-tests
@@ -13,8 +13,8 @@ set -e
 apk add --no-cache python3 py3-pip borgbackup postgresql-client mariadb-client
 # If certain dependencies of black are available in this version of Alpine, install them.
 apk add --no-cache py3-typed-ast py3-regex || true
-python3 -m pip install --upgrade pip==20.2.4 setuptools==50.3.2
-pip3 install tox==3.20.1
+python3 -m pip install --upgrade pip==21.3.1 setuptools==58.2.0
+pip3 install tox==3.24.4
 export COVERAGE_FILE=/tmp/.coverage
 tox --workdir /tmp/.tox --sitepackages
 tox --workdir /tmp/.tox --sitepackages -e end-to-end